1-(2,4,5-trichlorophenyl)ethan-1-one

  • Name: 1-(2,4,5-trichlorophenyl)ethan-1-one
  • CAS: 13061-28-4
  • Purity: 99%
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Details

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  • Molecular Formula: C8H5Cl3O
  • Molecular Weight: 223.486
  • Vapor Pressure: 0.0018mmHg at 25°C 
  • Refractive Index: 1.563 
  • Boiling Point: 292.7 °C at 760 mmHg 
  • Flash Point: 122.4 °C 
  • PSA: 17.07000 
  • Density: 1.425 g/cm3 
  • LogP: 3.84940 

1-(2,4,5-trichlorophenyl)ethan-1-one(Cas 13061-28-4) Usage

General Description

1-(2,4,5-trichlorophenyl)ethan-1-one, also known as triclocarban, is an antimicrobial compound used in various personal care products such as soaps, detergents, and body washes. It is a white to light yellow crystalline powder that has a chlorinated aromatic structure. Triclocarban has been widely used as an antibacterial agent due to its ability to inhibit the growth of bacteria and fungi. However, there is growing concern about its potential negative impact on human health and the environment, leading to restrictions on its use in some regions. Studies have shown that triclocarban can accumulate in the environment and may have endocrine-disrupting effects. As a result, there is ongoing research into alternative antimicrobial compounds with safer profiles.

InChI:InChI=1/C8H5Cl3O/c1-4(12)5-2-7(10)8(11)3-6(5)9/h2-3H,1H3

13061-28-4 Relevant articles

Fused thia-heterocycles via isothiocyanates. Part I. Facile synthesis of some new 1-benzothiopyran-4-one derivatives

Barhoumi, Lina M.,El-Abadelah, Mustafa M.,Sabri, Salim S.,Voelter, Wolfgang

, p. 369 - 375 (2017/05/16)

A selected set of new 4H-benzothiopyran-...

13061-28-4 Process route

acetyl chloride
75-36-5

acetyl chloride

1,2,4-Trichlorobenzene
120-82-1,63697-18-7

1,2,4-Trichlorobenzene

2,4,5-trichloroacetophenone
13061-28-4

2,4,5-trichloroacetophenone

Conditions
Conditions Yield
With aluminum (III) chloride; at 20 ℃; for 3h;
82%
With aluminium trichloride;
2,4,5-trichlorobenzoic acid
50-82-8

2,4,5-trichlorobenzoic acid

2,4,5-trichloroacetophenone
13061-28-4

2,4,5-trichloroacetophenone

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: thionyl chloride
2: benzene / Erwaermen des Reaktionsgemisches
With thionyl chloride; benzene;

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